FDA Approves Alternative to Surgical Castration for Pigs

April 27, 2011 — 

Pfizer Animal Health has announced that the U.S. Food and Drug Administration (FDA) has approved IMPROVEST® (gonadotropin releasing factor-diphtheria toxoid conjugate). Farmers have the option to use this safe and effective veterinary prescription product for temporary immunological castration and reduction of boar taint in intact male pigs intended for pork.

IMPROVEST is a protein compound that uses the pig's own immune system to provide the same effect as surgical castration, but much later in the male pig's life.

This technology is approved in 58 other countries around the world, including the European Union, Australia and Japan, under the related global brand, IMPROVAC®.

Pigs are given IMPROVEST via injection. The first dose primes the system and should be administered no earlier than nine weeks of age. The second dose should be administered at least four weeks after the priming dose.

Pigs should be sent to market no earlier than four weeks after the second dose of IMPROVEST to allow adequate time for reduction in the compounds responsible for off odor in pork. Marketing pigs on the IMPROVEST program more than eight weeks after the second dose may increase the risk of off odor in pork. Only trained, certified technicians will be permitted to administer the product as part of the quality assurance program.

As the product is gradually introduced, Pfizer Animal Health will work with veterinarians and their producer clients to help them adopt new nutritional guidelines and best handling practices to optimize growth for intact males.

Important Safety Information
IMPROVEST should not be used with female pigs, barrows or male pigs intended for breeding. Special care should be taken to avoid accidental self injection during administration of IMPROVEST. Accidental self injection could negatively affect reproductive physiology of both men and women. Therefore, pregnant women should not administer IMPROVEST and women of childbearing age, as well as men, should exercise extreme caution when administering the product. There is no risk, however, of these effects on an individual who consumes pork from pigs given IMPROVEST.

Additional product information will be available at http://www.PfizerPork.com/IMPROVEST.

Source: Pfizer Animal Health Press Release, PorkPoint