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Abstract: Global Seropositivity of Swine Leptospirosis: Systematic Review and Meta-Analysis

May 2, 2023 —

Leptospirosis is a major threat to public health worldwide; however, there is no study focused on global seropositivity in pigs. In this study, we grouped publications and performed a systematic review with meta-analysis to gather data related to swine leptospirosis seropositivity published globally. The search method initially used returned a total of 1183 results, of which 20 met all predefined criteria and were therefore included in this review. Meta-analysis with general data was performed and a combined seropositivity of 21.95% was found. Seropositivity was 36.40% in South America, 34.05% in North America, 22.18% in Africa, 17.40% in Oceania, 13.30% in Europe and 13.36% in Asia. The results suggest that there is high seropositivity for leptospirosis in pigs worldwide. Information compiled from this research is relevant to understanding the spread of leptospirosis globally. It is expected that these indicators will contribute to a better understanding of the epidemiology of the disease with a focus on its control and, consequently, on the reduction of cases in the human and animal population.

Gomes de Araújo H, Limeira CH, Viviane Ferreira de Aquino V, et al. Global Seropositivity of Swine Leptospirosis: Systematic Review and Meta-Analysis. Trop Med Infect Dis. 2023;8(3):158. Published 2023 Mar 5. https://doi.org/10.3390/tropicalmed8030158