Mapping Hotspots for Spread of PRRSV-2 Lineage 1 in the United States

August 14, 2022 — 

Porcine reproductive and respiratory syndrome costs the United States over $500 million annually (1). The repeated emergence of new genetic variants of PRRSV-2, the causative virus, reflects the failure of previous control efforts.

Within the United States, PRRSV-2 persistence is characterized by the co-circulation of numerous distinct variants defined by genetic variation of open reading frame 5 (ORF5), the major viral envelope glycoprotein coding gene. Although it is hypothesized that immune-mediated selection underpins its evolutionary dynamics, understanding spatial variability in selection pressures, variant emergence and spread is critical.

Read the full article in National Hog Farmer.

[Source: National Hog Farmer 9 August 2022]