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Bat-Origin Coronaviruses Expand Their Host Range to Pigs

Infections with bat-origin coronaviruses have caused severe illness in humans by 'host jump'. Recently, novel bat-origin coronaviruses were found in pigs. The large number of mutations on the receptor-binding domain allowed the viruses to infect the new host, posing a potential threat to both agriculture and public health.

Wang L, Su S, Bi Y, Wong G, Gao GF; Bat-Origin Coronaviruses Expand Their Host Range to Pigs; Trends Microbiol. 2018 Apr 18. pii: S0966-842X(18)30060-X. doi: 10.1016/j.tim.2018.03.001. [Epub ahead of print] PMID: 29680361 DOI: 10.1016/j.tim.2018.03.001